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by Aaron Christopher Segura
| Institution: | University of New Mexico |
|---|---|
| Department: | Mathematics & Statistics |
| Degree: | |
| Year: | 2022 |
| Keywords: | COVID-19; machine learning; breath signals; simulation; autoregressive moving average; Applied Mathematics; Mathematics; Statistics and Probability |
| Posted: | 3/25/2025 |
| Record ID: | 2290332 |
| Full text PDF: | https://digitalrepository.unm.edu/math_etds/170 |
This study compared the performance of machine learning models in classifying COVID-19 patients using exhaled breath signals and simulated datasets. Ground truth classification was determined by the gold standard Polymerase Chain Reaction (PCR) test results. A residual bootstrapped method generated the simulated datasets by fitting signal data to Autoregressive Moving Average (ARMA) models. Classification models included neural networks, k-nearest neighbors, naïve Bayes, random forest, and support vector machines. A Recursive Feature Elimination (RFE) study was performed to determine if reducing signal features would improve the classification models performance using Gini Importance scoring for the two classes. The top 25% of features determined by Gini Importance scores suggest that profiles from specific Volatile Organic Compounds (VOC) in patient breath may contribute to model performance.
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